VILLA SERENA

  • Room at Villa Serena

    Room at Villa Serena

  • Restaurant at Villa Serena

    Restaurant at Villa Serena

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An exclusive escape in the heart of the tropics at Villa Serena Hotel in Cayo Largo


In the heart of the unspoiled island of Cayo Largo, Villa Serena Hotel welcomes you to a haven of calm, elegance, and untouched nature. Breathtaking landscapes, endless beaches, vibrant tropical gardens, soothing ocean breeze, and discreet, warm service create the ideal setting. Whether you're here to celebrate love, explore nature, or slow down time, Villa Serena Hotel in Cayo Largo offers a tailor-made journey at the heart of a Caribbean secret.

Rooms, suites, and seaside pleasures

Peaceful havens with ocean views

Spacious, bright, and tastefully decorated, the rooms at Villa Serena Hotel in Cayo Largo are designed to offer an experience where relaxation and refinement blend seamlessly. Private balconies provide stunning sea views, perfect for starting the day with the sound of waves and a soft Caribbean breeze. Equipped with all modern comforts, air conditioning, television, refrigerator, full bathroom, and safe, these rooms are true sanctuaries of rest, offering serene, natural comfort and a deep sense of tranquility.

Elegant suites and personalized touches

The suites at Villa Serena Hotel in Cayo Largo embody the Caribbean art of living at its most sophisticated. Offering generous living space, breathtaking views, and a tranquil atmosphere, they are ideal for travelers seeking privacy and exclusivity in a romantic, intimate, and peaceful environment. Premium services include a responsive concierge available day and night, high-end welcome amenities, and tailor-made offerings to add a special touch of exclusivity to your stay.

Soothing facilities and paradisiacal pools

Surrounded by lush tropical gardens, Villa Serena Hotel in Cayo Largo offers facilities designed for rejuvenation and deep relaxation. A large saltwater pool overlooks the sea, while more secluded pools are nestled among the greenery. Lounge chairs, shaded areas, and open-air design create a relaxing space where every corner invites you to slow down and enjoy the calm atmosphere. Whether you prefer sunbathing or swimming, the facilities exceed expectations with beauty, comfort, and care.

Exquisite flavors and moments of well-being at Villa Serena Hotel in Cayo Largo

Gourmet delights in a tropical setting

At the restaurants of Villa Serena Hotel in Cayo Largo, cuisine is a celebration of taste, freshness, and vibrant local culture. Each colorful dish is prepared with carefully selected local ingredients and paired with international influences to offer a palette of authentic, bold flavors. From Cuban specialties to reinvented classics, the menus change with the seasons, providing a sensory journey to be savored facing the sea or the lush gardens. The chefs, passionate and endlessly creative, strive to surprise your taste buds with every memorable meal.

Refined atmosphere and sunset cocktails

Throughout the day, the bars at Villa Serena Hotel in Cayo Largo offer a wide selection of beverages to suit every taste, occasion, and mood. Sip a mojito by the sea, share a glass of wine by the pool, or try a signature cocktail crafted by skilled bartenders. In the evening, soft musical performances and local shows extend the experience in an atmosphere that remains elegant, relaxed, inspiring, and delightfully Caribbean. It’s the perfect place to end a day of escape, with a cocktail in hand and the horizon glowing above.

Spa inspired by tropical rituals

The spa at Villa Serena Hotel in Cayo Largo is a true haven of calm, balance, and rejuvenation. In an intimate, natural setting, let yourself be carried away by relaxing massages, personalized facials, or aromatic baths. Using natural, locally sourced products, each treatment is an invitation to deep peace and inner reconnection. The highly qualified staff gently guides you attentively throughout this unique wellness experience. A sensory journey that restores the body, soothes the mind, renews energy, and revitalizes the soul.

Fitness space between sea and nature

For guests wishing to stay active, the fitness center at Villa Serena Hotel in Cayo Largo offers a complete selection of modern, user-friendly equipment. Surrounded by greenery and bathed in natural sunlight and sea breeze, this space allows for exercise in an inspiring and calming environment. Whether it’s a morning cardio session or a few gentle stretches, you’ll find the motivation to move while recharging your energy and mood. 

Activities, events, and discoveries on the island

Active experiences with the rhythm of the sea

Villa Serena Hotel in Cayo Largo offers a wide range of exciting, inspiring, and memorable activities to enrich everyday: snorkeling in coral reefs, kayaking on calm waters, sunrise paddleboarding, or yoga by the beach. The hotel’s private beaches provide an ideal sanctuary for swimming, barefoot walks, and marveling at the untouched nature surrounding the property. Both adventurers and relaxation seekers will find happiness here. The Villa Serena Hotel team organizes tailor-made excursions to reveal the island’s hidden gems.

Unforgettable celebrations in a magical setting

Weddings, honeymoons, and private events find an exceptional, peaceful, and romantic setting at Villa Serena Hotel in Cayo Largo. Palm-lined beaches, blooming gardens, and starry skies become the backdrop for unforgettable moments. The dedicated event team takes care of every detail to personalize each moment and ensure a seamless, elegant, and perfectly orchestrated celebration. Every event is carefully designed to reflect your deepest wishes. Let the magic of the place elevate every meaningful moment of your life.

Cultural exploration and living heritage

Cayo Largo is also a land of meaningful encounters, local flavors, and strong traditions. Villa Serena Hotel in Cayo Largo invites you to discover the island from a new perspective: excursions to local villages, artisan workshops, regional food tastings, or visits to nature reserves with exotic animals. Each outing immerses you in Cuba’s vibrant, sincere soul. These authentic discoveries enrich your stay, revealing the country’s artistic, musical, culinary, and historical treasures.

Family holidays filled with laughter and shared moments

Families will find the perfect balance between relaxation and joyful group entertainment at Villa Serena Hotel in Cayo Largo. Supervised kids’ clubs, accessible water activities, creative workshops, bike rides, or group yoga sessions help create unique, meaningful, and lasting memories while respecting each person’s pace. The safe and caring environment encourages children and adults alike to thrive, bond, and grow together. It’s the perfect place to experience precious moments across generations and truly connect.

The promise of an exceptional stay at Villa Serena Hotel in Cayo Largo

Outstanding service in a protected natural setting

The family-like atmosphere and professionalism of the team make all the difference at Villa Serena Hotel in Cayo Largo. The attention to detail, constant kindness, and genuine passion for hospitality create a sense of closeness and immediate comfort. It’s this high level of service that transforms a simple stay into a deeply memorable experience. The team anticipates your needs with discretion, ensuring every moment is smooth, relaxing, and thoroughly enjoyable.

Ready to experience pure escape

Choosing Villa Serena Hotel in Cayo Largo means treating yourself to a blissful getaway in a pristine environment, where understated luxury meets heartfelt warmth. Let yourself be charmed by the Caribbean spirit, the richness of the landscapes, and the authenticity of an extraordinary welcome. Book your stay now and step into a world where each day becomes a cherished memory. Every moment spent at Villa Serena Hotel in this tropical haven will remind you that true luxury is time reclaimed.

    Clic on the supplier's logo to get more information about this hotel

    Address :
    Archipiélago de los Canarreos
    Cayo Largo
    Cuba
    69400
    Nearest Airport
    Cayo Largo del Sur (CYO)
    Distance from airport
    10 km
    Time from airport
    10 min
    1
    Restaurants
    1
    Buffets
    2
    Bars
    2
    Pools
    Located on beach
    Adults only
    Mini Club
    Spa
    Casino
    Rooms
    59 Rooms
    Voltage
    110 v
    Previous hotel names:
    • Hotel Isla Del Sur

    Frequently Asked Questions

    The Villa Serena in Cayo Largo Cuba offers free WiFi in the lobby.
    The Villa Serena in Cayo Largo Cuba offers 1 buffet, 1 à la carte/snack and 1 snack.
    The Villa Serena in Cayo Largo Cuba is located directly on the beach.
    The Villa Serena in Cayo Largo Cuba is not exclusive to adults, it is open to people of all ages.
    The Villa Serena in Cayo Largo Cuba is an all-inclusive hotel offering 2 restaurants, 2 bar and 2 swimming pool.
    The Villa Serena in Cayo Largo Cuba is 10km from Vilo Acuña CYO airport, about 10 minutes away.
    The Villa Serena in Cayo Largo Cuba offers a program of activities and entertainment during the day and evening, volleyball, dance classes, board games, table tennis, aerobics, etc.
    The Villa Serena in Cayo Largo Cuba offers no activity program for children.
    Villa Serena in Cayo Largo Cuba does not include golf.
    The Villa Serena in Cayo Largo Cuba has 2 swimming pools.
    The Villa Serena in Cayo Largo Cuba is a hotel offering light entertainment day and evening.
    The Villa Serena in Cayo Largo Cuba does not have a gym or spa ($).
    The Villa Serena in Cayo Largo Cuba has 59 rooms.
    The Villa Serena in Cayo Largo Cuba offers excursions at extra cost, such as catamaran rides, snorkeling and days on secluded beaches. Many additional options are available.
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